Viagra has become one of the most popular trade names for the drug Sildenafil Citrate, created by Pfizer in 1989. This prescription medication is used for the treatment of erectile dysfunction and pulmonary arterial hypertension.

The physiological contrivance of an erection involves the secretion, internally, of nitric oxide, into the body when sexually aroused. Nitric Oxide then initiates an enzyme known as guanylate cyclase. These two things together increase the secretion of another enzyme known as cyclic guanosine monophosphate. The enzyme makes the muscles relax, in turn expanding or dilating the blood vessels that allow for increased blood flow.

However, there are other enzymes which can inhibit the cyclic guanosine monophosphate, which is what causes ED.

Viagra stimulates the effect of nitric oxide by inhibiting enzymes responsible for the degeneration of cyclic guanosine monophosphate in the penis. This allows for more creation of the afore mentioned enzyme so that more blood can flow into the penis and remain for longer periods of time, hence extending and aiding in creating erections.

How Does Viagra Affect the Body?

Viagra works to enhance and stimulate erections. This is why it is used as a treatment of symptoms for erectile dysfunction. The drug will only work if sexual stimulation is present. Without it, the drug is essentially useless for ED. The average time for onset of the drug to work is anywhere between twenty and forty-five minutes, depending on the dosage and the individual.

Typical Dosage

The starting dose for most individuals is fifty milligrams. After the pill is swallowed, Viagra is quickly absorbed into the system. Depending on the size of the person and their metabolism, as well as the method of taking the medication, it can work more quickly or more slowly.

Proper dosing must always be properly determined by your doctor. Never try to self-dose without consulting with your physician first, who will be able to direct you to the proper amount for your weight and specific situation.

It is important to note that one must seek medical assistance if an erection lasts more than four hours. This is considered a medical emergency and can lead to tissue damage and scarring in the penis. If this happens, take it very seriously.

Viagra is at its peak one hour after administration, and after four hours the blood levels are half of that when it was at its peak. That doesn’t mean that an erection can’t occur at or after four hours. It’s a very individual experience and depends on body type, metabolism, and severity of erection problems. Factors such as tiredness or intake of alcohol can also play a role in the effectiveness of your dose.

Half a day after taking the medication it is still possible to have an erection. These erections won’t last as long as in previous hours, probably about half the time. Viagra is still in the system after twelve hours, and trials have shown that better erections occur on the medication after this time frame than if a placebo was taken.

What Can Affect the Response of the Drug?

This largely depends on the dosage being taken. Sometimes your exact ideal dose may take some experimenting and you will need to continue to talk with your doctor until you get satisfactory results.

Additionally, timing of when you eat and take the medication, as well as if you have any alcohol in your system all may play roles in slowing or effecting the results of the medication. Extra stress may do so as well.

Be sure to always talk with your doctor about any questions or difficulties you have with Viagra.